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5.2 Integrative oncology trials and protocols The American Society of Clinical Oncology (ASCO) and the Society for Integrative Oncology have jointly formulated evidence-based approaches to the integration of complementary and alternative medicine (CAM) as applicable to the management of anxiety, depression, and fatigue and the use of cannabinoids and cannabis in the oncology setting

doi: 10.1016/j.jchromb.2009.07.001

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First of all, intracellular iron generally exists in the form of Fe 2+ , which can produce OH through the Fenton reaction, and then react with polyunsaturated fatty acids in the plasma membrane to produce ROS, resulting in iron-regulated death