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Curcumin represses colorectal cancer cell proliferation by triggering ferroptosis via PI3K/Akt/mTOR signaling

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Long-term safety data beyond 90 days is limited even for the individual compounds

Selenium: Selenium is a trace element essential to generate glutathione that protects cellular membranes

Since endothelium plays an important role in regulating vascular tone and cell proliferation, it is likely that endothelial dysfunction might initiate the sequence of events that results ultimately in structural changes