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This may be even more important in light of theCOVID-19 pandemic as the use of tobacco products likely increases the risk for COVID-19 associated cardiovascular and other severe complications in smokers and vapers.

Moreover, a consequence of reducing nicotine dependence to subjective craving to smoke is that the results of the "hooked on nicotine" research program cannot be compared to results of studies that use the conventional, DSM or ICD conceptualization of nicotine dependence