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Summary: There is no authorised UK reconstitution ratio for retatrutide, as it remains an unlicensed investigational compound with no approved MHRA guidance, SmPC, or NHS prescribing pathway

Chem Rev 121:32973351 White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H et al (2019) Discovery of an SSTR2-targeting maytansinoid conjugate (PEN-221) with potent activity in vitro and in vivo