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If the reason for fatigue or low energy is unclear, the team can help you decide whether B12 is appropriate or whether primary care follow-up is the better next step

Answer: The best injection site for a B12 shot can depend on personal comfort and ease of access

Consult a healthcare provider before supplementing if you: Take blood thinners (vitamin D affects clotting) Use metformin, or proton pump inhibitors (both affect B12 absorption) Have kidney disease (impairs vitamin D metabolism) Have a history of kidney stones (excess vitamin D increases risk) Are being treated for any chronic condition Testing first ensures you get the right dose

People with pernicious anemia or people who cannot absorb vitamin B 12 from their intestines will need injections of vitamin B 12 every one to three months indefinitely