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P53 phosphorylation at Ser15 enhances the affinity of both FOXO4 and FOXO4-DRI for p53 TAD2 explaining the preferential engagement of FOXO4-DRI with the hyperphosphorylated p53 characteristic of senescent cells

EP300 usually regulates transcription factors mainly through acetylation and further activates cell cycle-related genes, thus affecting the progression of cancers 39

Here's a comparative analysis between the two peptides: Molecular Structure BPC-157 is a synthetic peptide made of 15 amino acids that does not share homology with any known endogenous human peptides [2]

I personally prefer doing them myself as I can clinically assess the patients immediately after the injection as part of a Neers test and also then I know whether I have achieved a good bursal injection or not