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This was Citius second try for FDA approval, after the regulator rejected Lymphir in July 2023, outlining the need for enhanced product resting requirements. In its resubmitted data package, the company included findings from the from the Phase III Study 302 trial, where treatment with the drug led to an objective response rate of 36.2%, with 8.7% reaching complete response

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Modifications for grapplers with shoulder or elbow injuries might include positional drilling without resistance, focusing on guard work that avoids the injured limb, partnering with lighter or more controlled training partners, and drilling escapes and defensive positions that protect the injury