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Putative mechanisms by which vitamin D may be beneficial in FM include: Modulation of nociceptive transmission in skeletal muscles, and its deficiency may lead to hyperinnervation and hypersensitivity to musculoskeletal pain

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Adult Dosing Dosage may vary based on different medical indications: For the initial treatment of vitamin B12 deficiency, the usual dose is 1000mcg SC/IM, given once a day for 1 week, followed by 1 dose a week for 1 month