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Moreover, p53 serves as a critical mediator to affect the activity of system XC- by downregulating SLC7A11 transcription and augmenting the expression of spermine/spermidine-n1-acetyltransferase 1, raising the level of ALOX15 and boosting the accumulation of cytoplasmic peroxides (Ou et al., 2016
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With the deepening of urbanisation, ecological space significantly crosses multi-level administrative boundaries, which involves the synergistic application of multiple governance subjects, complex governance arenas and diversified governance tools
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