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doi: 10.3389/fgene.2020.630186 Received 16 November 2020 Accepted 21 December 2020 Published 21 January 2021 Volume 11 - 2020 Edited by Ilia Stambler, Independent Researcher, Tel Aviv, Israel Reviewed by Idan Shalev, Pennsylvania State University (PSU), United States

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Next, we evaluated the functional role of BACH1 in the proliferation and tube formation phenotype of BPC157-treated cells

The PTC cell lines selected for the in vitro experiments represent some of the most common mutational signatures observed in thyroid cancer, particularly BRAF V600 E is found in more than 60% of PTCs and purports more aggressive tumor phenotype