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These articles report KEs such as oxidative stress (e.g., reactive oxygen species), DNA damage (e.g., strand breaks, oxidative lesions, DNA adducts), and altered genes frequently associated with lung tumorigenesis, such as TP53, KRAS, and EGFR

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"Several liver diseases like acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also be accompanied by an increase in circulating cobalamin," according to the aforementioned researchers

Accordingly, there is the counteraction of doxorubicins chronic heart failure (both prevention and reversal) [48]