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Unlike oral supplements, which have to go through the digestive system and can be affected by factors like stomach acid and digestive enzymes, injections deliver the vitamin directly into your bloodstream

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According to WebMD, The more common B12 injection side effects are: Swelling at the injection site Mild dirhhea Itching Swelling in the body Low potassium (weakness, irregular heartbeat) There is a case report of an anaphylactic reaction to a B12 injection in a 55 year old women receiving cyanocobalamin, but these reactions are thought to be rare