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Combining standard-therapy secukinumab with a one-time dose of guselkumab may provide a synergistic effect by targeting different cytokines involved in the pathogenesis of psoriasis

10.1016/0005-2760(90)90118-H 61 WuK

This work was supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) Grant Number JP15K19036 (SH), JSPS Grant-in-Aid for Young Scientists Grant Number JP19K16271 (SH), Japan Science and Technology Agency (JST) ACT-X Grant Number JPMJAX201A (SH), RIKEN FY2018 Incentive Research Projects (SH), and Naito Grant for female scientists after maternity leave (SH)

DATS protected cardiac cells in vitro and in experimental diabetic rats from high glucose-induced oxidative stress and apoptosis by inducing PI3K/Akt-dependent Nrf2 antioxidant signaling (23)