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However, the US federal governments view was that if health claims were being made in respect of substances not derived from a natural plant, such as tobacco, then they would be deemed unproven drugs, tangling the companies up in red tape

Those sales numbers correlate with what the Centers for Disease Control and Prevention have seen over the same period

In Japan and the U.S., around 12-13 percent of the population smokes, and in the EU, the figures are generally even higher (around 25 percent in France, around 20 percent in Spain, around 17 percent in Denmark, and around 11 percent in the UK)

Smoking doesn't cause wrinkles immediately of course, but it only takes a couple of years before cigarettes start taking their toll