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Coder Note AHA Coding Clinic advice is the official resource for coding guidance and supersedes individual facility guidelines where there is a conflict

Informed consent was obtained from all participants for research purposes

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Long-Term Substitutions Patients seeking the antioxidant or anti-inflammatory benefits of GTE during isotretinoin therapy can consider: Dietary brewed green tea at 1 to 3 cups per day with meals (not supplements) Topical EGCG formulations, which bypass hepatic first-pass entirely and have shown benefit in acne management in the JID 2012 RCT [11] Reassessing GTE supplementation after isotretinoin completion and a minimum 4-week washout period Drug Interactions With Isotretinoin Beyond GTE: Context Matters GTE is not the only supplement concern during isotretinoin therapy