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10.1016/S1474-4422(09)70293-5 Lancet Neurol

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Our findings describe a role for mitochondrial plasticity as a mechanism for acute 5FU tolerance in CRC cells: mitochondrial changes acutely adopted by CRC cells in response to 5FU-based standard-of-care treatment result in increased mitochondrial biogenesis, which provides metabolic support for increased pyrimidine scavenging by UCK2 to resolve nucleotide stress

Remarkably, the as-assembled PIC device using OCMS as an anode and 3DPC as a cathode exhibited a high energy of 140.7 W h kg 1 at 643.8 W kg 1 , with a long cycle stability over 8500 cycles