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In the CUMS model, the ratio of microtubule associated protein 1 light chain 3 (LC3)-II/I was significantly decreased, and the expression of p62 protein was markedly increased, indicating a decrease in autophagic activity in the rat hippocampus, while the autophagic activity was over-activated in the PFC

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[14], [15] Experiments on oral administration of sugar syrup with BPC-157 into the GI tract of honey bees have reported positive effects on Nosema Ceranae invasions and so-called CCD syndrome of colony collapse disorder