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Multiple treatment modalities for hyperpigmentation that shift eumelanin to pheomelanin synthesis exist

Additionally, glutathione has been used in the management of conditions such as autism, chronic fatigue syndrome, and to support detoxification in cases of poisoning or overdose

While a constant exposure of quinone is not necessarily representative of an in vivo scenario, it is however, much more representative of an in vitro situation, whereby a constant source of quinone is essentially available in the extracellular media during cell culture 27

J Nanobiotechnol 15:112 Zhang L, Zhou L, Du J, Li M, Qian C, Cheng Y, Peng Y, Xie J, Wang D (2014) Induction of apoptosis in human multiple myeloma cell lines by ebselen via enhancing the endogenous reactive oxygen species production