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Considering c-MET in aspects of cell signaling network through cross-talking with EGFR, VEGFR-2 and other signaling molecules, it is necessary to develop antibodies that are able to inhibit simultaneously two signaling cascades to achieve maximal therapeutic activity [77, 119]

Further, given its potential proliferative effects, ipamorelin is not advised for subjects with cancerous conditions, as it might intensify disease progression

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Growth hormone secretagogues produce full-spectrum growth hormone effects including potential appetite stimulation, IGF-1 elevation, and systemic metabolic changes affecting multiple tissues