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Moreover, loss of JAM-A resulted in elevated mucosal and serum immunoglobulin A that was dependent on CD4(+) T cells and tumor growth factor-

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The enzymes responsible for this digestion (pepsin in the stomach, trypsin and chymotrypsin from the pancreas in the small intestine) are highly efficient and rapidly degrade most therapeutic peptides to pharmacologically inactive fragments before they can act on mucosal tissue

Esta propiedad est directamente relacionada con su origen gstrico: resiste la degradacin enzimtica en el estmago, lo que abre la va a una administracin oral una ventaja considerable frente a otros pptidos que requieren imperativamente una inyeccin