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Because of the damage doxorubicin does, it creates large numbers of senescent cells

An important feature of astrocytic interaction with the BBB are the perivascular end feet which closely interact with the vascular walls and almost completely cover the entire cerebral vasculature [48]

Administered for the first 2-3 years, these bioregulators were associated with changes in cardiovascular, endocrine, immune, and nervous system function, as well as homeostasis and metabolism

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