Neither product is risk-free for a non-smoker
In answer to the more direct question of how much nicotine per day is safe, a reasonable starting point might be, "How much nicotine might it take to poison someone?" The ECHA currently gives an "acute toxicity estimate" (ATE) for nicotine via the oral route to be 5 mg/kg bw [7] , meaning 5mg of nicotine for every kilogram of bodyweight of the person consuming the nicotine
The role risk of cigarette smoking, alcohol consumption, sleeping disorder, and mental health with hearing loss among stroke patients Abdulbari Bener, Ahmet Erdoan, Lima Oria, Hajira Karim, Lrf Hanolu Tobacco Prevention & Cessation 8
That decision was based on the FDAs determination that the new products offer greater benefits to population health than risks. The data, said Matthew Farrelly, director of the Office of Science at the FDAs Center for Tobacco Products, show that these nicotine pouch products meet that bar by benefiting adults who use cigarettes and/or smokeless tobacco products and completely switch to these products. Nicotine pouches contain substantially lower amounts of harmful constituents than cigarettes, the FDA noted
