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Epithalon (also known as Epitalon or Epithalone) is a synthetic tetrapeptide composed of four amino acids: alanine, glutamic acid, aspartic acid and glycine (Ala-Glu-Asp-Gly)

Similarly, the reduction in NCOA4 expression, a gene involved in the autophagic degradation of ferritin, known as ferritinophagy [36], further supports melatonins role in modulating iron metabolism to mitigate ferroptosis risk

There was a positive trend in the Composite SLE Responder Index in the Intention-to-treat (ITT) cohort, and post-hoc analysis showed that the BILAG secondary endpoint was met for a number of subgroups dosing levels, including low or no steroids, seropositivity, and patients with 2 grade BILAG improvement

Zat ini banyak terdapat dalam sel hewan dan tumbuhan, terutama berperan dalam membersihkan spesies oksigen reaktif dan radikal bebas, melindungi sel dari kerusakan oksidatif, dan berperan dalam proses detoksifikasi tubuh