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The only human trial ever registered (NCT02637284) was cancelled in 2016 without publishing results

EDS primarily affects your connective tissues, such as collagen, in locations around your body, including in your joints

Meanwhile, ROCK can enhance the transduction of transforming growth factor-1/suppressor of mothers against decapentaplegic homolog signaling [40], thereby inducing endothelial-to-mesenchymal transition, increasing fibrosis markers, and structural remodeling of the microvasculature in the CC [41]

The products are only available to institutions or individuals that are associated with research or laboratory activities.