Melarsoprol and arsenic trioxide increase cell death on doxorubicin-resistant human leukemia and myeloma cells by regulating expression of bcl-2 apoptosis regulatory family

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Numerous studies indicate that, in many tumors, flux through the reductive carboxylation pathway toward lipogenesis can exceed the flux of glutamine oxidation through the citric acid cycle 226,227,228,229
doi: 10.1007/978-981-99-1718-1_17 36 MacvaninMTGluvicZZafirovicSGaoXEssackMIsenovicER