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Ayoub E, PhD, Montoya RH, BS, Mohanty V, PhD, Walter W, PhD, Patsilevas T, BS, Issa GC, MD, Borthakur G, MD, Chen K, PhD, Konopleva M, MD, PhD, Navin N, PhD, Haferlach T, MD, Andreeff M , MD, PhD

Calcium spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina platensis

Clinical investigation to support new uses generally requires an Investigational New Drug (IND) application with appropriate chemistry, manufacturing, and controls, nonclinical safety, and human data

Inactivation of the dnaK gene in Clostridium difficile 630 Deltaerm yields a temperature-sensitive phenotype and increases biofilm-forming ability