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Effect of electronic cigarettes on smoking reduction and cessation in Korean male smokers: a randomized controlled study

A partial list of those excluded includes those suffering from cardiovascular disease, alcohol abuse, major depression, panic disorder, systolic blood pressure greater than 150 or diastolic pressure greater than 95, a history of cancer, a body mass index (calculated as weight in kilograms divided by height in meters squared) of less than 15 or higher than 38

While this may be part of the traditional smoking experience for many, it also releases a large amount of harmful substances

A second important cause was the fact that tobacco was indigenous to the [3]soil and climate of Virginia