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Routes of administration include intraventricular, intracarotid, intravenous and intraperitoneal injection each producing different effective central exposures of an unstable peptide

Shown is the phagocytosis by THP-1 cells (panel A) of ring-infected and non-infected GR-deficient RBCs from the index patient, brother (individual 2) and sister (individual 3) of the index patient, and from normal GR-sufficient controls

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Certain muscle groups observed in murine models, including the rectus abdominis, psoas major , and paraspinal muscles, showed a more pronounced increase in muscle density and volume, as well as a reduction in intramuscular fat content, than those observed in controls