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[1] Some compounders suggest adding B12 to tirzepatide formulations based on theoretical concerns about vitamin B12 absorption, though it's important to note that clinical evidence specifically linking tirzepatide to B12 deficiency is lacking

AOD 9604 Studies on Obesity Models In obese murine models, both growth hormone and AOD 9604 have been linked to reductions in body fat mass, though the outcomes appeared different in lean models

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(More information) The long-term use of certain medications, such as inhibitors of stomach acid secretion and the anti-diabetes drug, metformin, can adversely affect vitamin B 12 absorption