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FSHR and LHR are both G-protein coupled receptors (GPCRs) that transmit the intracellular cascade via adenylate cyclase activity, cAMP accumulation, with subsequent activation of PKA, which then phosphorylates the transcription factor CREB (cAMP response element binding protein)

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Skin appearance fluctuates for reasons entirely unrelated to any product: sleep, hydration, stress, hormonal cycles, weather, and diet all visibly affect skin week to week