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The authors speculated that peer-led interventions may resonate to a greater extent with young people due to greater perceived credibility of peers than of adults or professionals, in part due to shared social status, cultural background and being embedded within the same social groups and communities

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ABBREVIATIONS MT melatonin MTV melatonin vape THC tetrahydrocannabinol CBD cannabidiol hBECs human bronchial epithelial cells ALI airliquid interface GSEA gene set enrichment analysis IL-8 interleukin-8 IP-10 interferon gamma-induced protein 10 MCP-1 monocyte chemoattractant protein-1 MCP-4 monocyte chemoattractant protein-4 MDC macrophage-derived chemokine MIP-1 Macrophage inflammatory protein-1 MIP-1 Macrophage inflammatory protein-1 TARC thymus and activation-regulated chemokine IFN- interferon- IL-10 interleukin-10 IL-12p70 interleukin-12p70 IL-13 interleukin-13 IL-1 interleukin-1 IL-2 interleukin-2 IL-4 interleukin-4 IL-6 interleukin-6 TNF- tumor necrosis factor- GM-CSF granulocyte-macrophage colony-stimulating factor IL-12p40 interleukin-12p40 IL-15 interleukin-15 IL-1 interleukin-1 IL-7 interleukin-7 VEGF vascular endothelial growth factor Footnotes This work was completed as part of an honors thesis by K.D.S

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