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doi: 10.7150/thno.63396 186 FengQXiaWWangSDaiGJiaoWGuoNet al

Moreover, oxidative damage to mitochondrial DNA (mtDNA) results in the release of mtDNA into the cytosol, where it triggers Toll-like receptor 9 (TLR9) and inflammasome activation, leading to further production of pro-inflammatory cytokines and recruitment of immune cells 67

Effects of -tocopherol and -carotene supplementation on cancer incidence and mortality: 18-year postintervention follow-up of the alpha-tocopherol, beta-carotene cancer prevention study

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