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Accumulation of trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid in prostate cancer due to androgen-induced expression of amino acid transporters

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S4D), we observed a strong collective decrease in the intracellular levels of the glycolytic intermediate 3-PG in response to 6 Gy irradiation ( p = 0.014), as well as downstream intracellular levels of serine and glycine metabolites ( p = 0.041 and p = 0.025, respectively, Fig