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[] Despite the benefits of using DFO to treat a variety of human diseases, essentially iron overload-associated pathologies, administration of this siderophore can result in certain adverse effects, which encompass failure of human development, bone dysplasia, retinal pigment epithelium modification, visual impairment, decreased night vision as well as impairments to the cardiovascular, respiratory, gastrointestinal, renal, cutaneous and neurological systems
Previous reports have shown the reduction of aldehydes into alcohols using NADH as a hydride source 15 , NAD + into NADH using formate as a hydride source 16 , pyruvate into lactate using formate as a hydride source 17,18 , or ally alcohols into ketones 19