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Improved understanding of the metabolic and communication routes that are affected by disease could provide new mechanistic insights into the pathogenesis of kidney diseases and potentially enable targeted dietary or pharmacological interventions

In other words, it is not a synthetic invention so much as a naturally occurring signaling molecule that researchers have tried to understand and, in places, to study therapeutically

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Additionally, there is proof that the excitatory amino acids, such as aspartate and glutamate, can alter the way the pituitary-thyroid axis secretes hormones [92, 93] Also, trace elements have shown to have impact on thyroid function