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& Harper, M

These reactive species are necessary in small amounts for processes like cell signaling, but when overproducedoften due to poor lifestyle habits like smoking, an unhealthy diet, or exposure to pollutionthey start to attack and damage healthy cells

Collectively, these factors establish a transcriptional framework that governs the core machinery of autophagy initiation, progression, and organelle turnover, integrating stress signals and nutrient availability into precise gene expression responses essential for cellular homeostasis and adaptation

Research in APP/PS1 Alzheimer's mice demonstrates that Dihexa treatment markedly reduces activation of astrocytes and microglia, the brain's primary inflammatory cells