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Life Sci 76:345357 Tonner PH, Scholz J, Lamberz L, Schlamp N, Schulte AM, Esch J (1997) Inhibition of nitric oxide synthase decreases anesthetic requirements of intravenous anesthetics in Xenopuslaevis

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As a general rule, the average speed of metabolism (in which the alcohol is fully broken down and no longer present in the blood) will be slower the smaller a man is