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Cancer Cell 2005;8:311-21

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Figure 2 4.1 Imaging of Gln metabolism predicts treatment response Abnormal Gln metabolism has facilitated the use of non-invasive imaging techniques for early tumor diagnosis and treatment monitoring, such as 18F-(2S,4R)-4-fluoroglutamine (18F-FGln) PET and L-(71)

Furthermore, metformin combined with 1.8 Gy radiation significantly increased the proportion of SW837 cells in late apoptosis, when compared to unirradiated metformin treated cells ( Figure 3D )