Delivery of oat-derived phytoceramides into the stratum corneum of the skin using nanocarriers: Formulation, characterization and in vitro and ex-vivo penetration studies
Once p53 is freed, it moves out of the nucleus toward the mitochondria and sets off the intrinsic apoptosis pathway (a caspase-driven self-destruct program)
10.1186/s12943-020-01258-7 Summary Keywords ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking Citation Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S and Yao J (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms
Chromatographic separation was performed using a Waters ACQUITY UPLC BEH C18 column (1.7 m, 2.1 mm 100 mm, Waters, USA), with the column temperature maintained at 45 C