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29 Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 Reversible metabolism via enterohepatic cycling Liu and Smith, Current Drug Metabolism, 2006EHC is not irreversible elimination, thus it acts as a distribution compartment for some drugs

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Although similar doses of glucoraphanin and glucoerucin were given in the sprouts and supplement, the total amounts of SFN and ERN metabolites in the plasma and urine were much lower in the supplement group compared to the sprout group.[23] The subjects got more sulforaphane out of raw sprouts than the supplement