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This explains why in children with delayed puberty the administration of T produces an increase in the pituitary reserve of GH, which is not observed when a non-aromatizable androgen, such as oxandrolone, is administered

PRPP synthetase is the enzyme responsible for the synthesis of the activated ribose (5-phosphoribosyl-1-pyrophosphate, PRPP) necessary for the de novo synthesis of purine and pyrimidine nucleotides

Association Between PD and CKD An increasing number of epidemiological and clinical data show that there is a correlation between periodontitis and CKD (Table 1), and the occurrence of periodontitis can have an impact on kidney tissue, function, and damage

doi: 10.1007/s00018-018-2745-8 186 ScalconVBindoliARigobelloMP