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Erythropoietic protoporphyria , caused by ferrochelatase deficiency producing phototoxic protoporphyrin IX accumulation in erythrocytes, plasma, and skin , provides a research model for studying MC1R-mediated photoprotection in a disease context where protection from visible light-induced phototoxicity is the primary biological endpoint

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452 Recently the role of astrocytic protein SAPAP3, encoded by Dlgap3 gene, in pathophysiology of OCD was suggested based on in depth analysis of astrocytic proteome