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The high BBB-crossing efficiency of rAAV-PHP.B and rAAV-PHP.eB is due to their interactions with the LY6A (also known as SCA-1) protein expressed on the brain microvascular endothelial cells (BMVEC) of the mouse BBB [167]
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Sleep Induction & EEG Changes: Delta sleep-inducing peptide (DSIP): an endogenous regulator of sleep and circadian rhythms (PubMed) Endocrine & Hormonal Modulation: Effects of DSIP on the release of LH and GH in laboratory models (PMC / NIH) Stress Response & Adaptation: The role of DSIP in the mechanisms of resistance to stress (PubMed) Antioxidant & Neuroprotective Effects: DSIP as a modulator of antioxidant enzyme activity in the brain (ScienceDirect) Metabolic & Physiological Regulation: Delta sleep-inducing peptide (DSIP): Review of biomedical properties (PubMed) Product Name: DSIP (Delta Sleep-Inducing Peptide) Molecular Formula: CHNO Molecular Weight: 848.81 g/mol Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu Form: Lyophilized (freeze-dried) powder Purity: 99% (HPLC verified) Appearance: White to off-white powder Quantity per Vial: 5 mg
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