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2.5 Quantification of oxidative phosphorylation and glycolysis The Seahorse XF96 Extracellular Flux Analyzer (Seahorse Bioscience, North Billerica, MA, United States) was utilized to measure real-time integrated cellular oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) as previously outlined (Lan et al., 2018

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CagriSema also reduced HbA1C scores on average by 1.91%-points compared with 1.76%-points for semaglutide