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Brian King, a deputy director at the Centers for Disease Control and Preventions Office on Smoking and Health, worries IQOS could make tobacco acceptable again

(AP Photo/Orlin Wagner) (ASSOCIATED PRESS)5 / 13Bill Parcells UNITED STATES - DECEMBER 29: New York Giants' Head Coach Bill Parcells draws from his cigarette during a news conference., (Photo by Dan Farrell/NY Daily News Archive via Getty Images) (NY Daily News via Getty Images)6 / 13Jerry ColemanUNITED STATES - JANUARY 01: New York Yankee 2nd baseman Jerry Coleman in locker room during spring training

Mitochondrial changes in PBECs from COPD patients compared to PBECs from (never-) smoking individuals In order to assess whether long-term smoking also results in (persistent) structural changes in epithelial mitochondria in COPD, we studied mitochondrial alterations in PBECs derived from severe ex-smoking COPD GOLD stage IV patients and age-matched never-smoking and smoking controls