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We believe that the lack of significant difference between the spinal sporadic MMNST cases and our SSP-MMNST ones may arise from the small sample size available
Many commercial preparations contain additional ingredients such as: Sorbitol or mannitol sugar alcohols used as sweeteners in some tablets that can cause osmotic diarrhoea when consumed in larger quantities, though the amounts in typical supplements are usually too small to cause symptoms alone [13] [14] Binding agents and fillers including lactose, which may cause symptoms in people with lactose intolerance, though tablet quantities are typically small Other additives various excipients that some individuals may be sensitive to The dose and frequency of supplementation may also influence tolerability
GrimmTChovanovZMuchovJSumegovKLiptkovADurackovZet alInhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)
Baharoglu Z
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