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Plant Physiol Biochem 166:448458 Huang S, Van Aken O, Schwarzlnder M, Belt K, Millar AH (2016) The roles of mitochondrial reactive oxygen species in cellular signaling and stress response in plants

PLoS ONE 7 , e34233 (2012)

Neither has completed comprehensive Phase 3 safety trials for tissue healing, so long-term human safety data remains limited for both

In an experiment with mouse ovaries, treatment with antioxidant pyrroloquinoline quinone efficiently decreased ROS production, alleviated oxidative stress, relieved mtDNA damage, and increased ATP production