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Our literature review has shown studies reporting tau deposits in tissue samples of the brain from autopsies of COVID-19 patients compared to the control group, and the in-vitro human brain organoid model has shown aberrant phosphorylation of tau protein in response to SARS-CoV-2 infection
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These insights underscore the therapeutic potential of targeting EMT-associated pathways to mitigate renal fibrosis, emphasizing the need for precise modulation of cadherin dynamics and TGF- signaling pathways