10.1186/s12951-021-01058-1 Summary Keywords ferroptosis, atorvastatin, cardiomyocytes, lipid peroxidation, ROS Citation Zhang Q, Qu H, Chen Y, Luo X, Chen C, Xiao B, Ding X, Zhao P, Lu Y, Chen AF and Yu Y (2022) Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis
BPC-157 (short for Body Protection Compound 157) is a laboratory-made, synthetic peptide made up of 15 amino acids
Illness/infection can trigger inflammation by proinflammatory cytokines increasing
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 6-hydroxydopamine (6-OHDA), and 5-S-cysteinyl-dopamine (CysDA) models each target dopaminergic neurons and increase oxidative damage to the brain, providing valuable insight to the efficacy of mitigating oxidative stress as a mechanism of sulforaphanes neuroprotective effects