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RNA sequencing and pathway enrichment analysis show FOXO4-DRI significantly downregulates extracellular matrix-receptor interaction pathways, including fibronectin (Fn1), tenascin C (Tnc), and thrombospondin 2 (Thbs2), all critical components of fibrotic tissue architecture

Alcohol is a diuretic, meaning it increases urine output and depletes your body's water stores

The alkylating chemotherapeutic temozolomide induces metabolic stress in IDH1-mutant cancers and potentiates NAD(+) depletion-mediated cytotoxicity

While several elegant methods have so far been developed for GST activity assay [5, 6], these methods are limited by the expensive materials, sophisticated instruments, or their time-consuming experimental procedures